Figure 3From: Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists MAGEA3 and ZFP3 CGI methylation and expression with 5-aza-dC treatment. Figure 3A illustrates hypomethylated cytosines at the TSS in otherwise hypermethylated CpG island and the corresponding expression (B). Figure C and D shows CGI hyper-methylation and expression of the temporarily reactivated ZFP3 gene in HT29 cells.Back to article page