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Table 3 Health-related quality of life in patients with early-onset and late-onset colorectal cancer

From: Comparative characteristics of early-onset vs. late-onset advanced colorectal cancer: a nationwide study in China

 

Number of items

Overall (N = 4572)

EOCRC, < 50 years (N = 991)

LOCRC, ≥ 50 years (N = 3705)

P value

Overall HRQOL*

 

128.18 (24.72)

127.63 (24.52)

128.33 (24.77)

0.441

FACT-C¶

36

    

Physical well-being

10

31.53 (5.85)

31.25 (6.12)

31.61 (5.77)

0.082

Social/Family well-being

7

22.98 (5.69)

23.04 (5.61)

22.97 (5.71)

0.722

Emotional well-being

5

14.89 (4.33)

14.75 (4.49)

14.92 (4.28)

0.262

Functional well-being

7

14.69 (6.95)

14.85 (6.84)

14.65 (6.98)

0.410

Colorectal cancer subscale

7

17.79 (4.55)

17.90 (4.48)

17.76 (4.57)

0.368

EORTC QLQ-C30

9

    

Functional scales and/or items¶

Physical

1

3.44 (1.02)

3.60 (0.90)

3.39 (1.05)

< 0.001

Cognitive

1

3.10 (1.00)

3.10 (1.03)

3.11 (0.99)

0.924

Emotional

2

6.24 (1.79)

6.05 (1.91)

6.30 (1.76)

< 0.001

Social

2

5.25 (2.20)

5.04 (2.30)

5.31 (2.17)

0.001

Symptom items§

Fatigue

1

0.89 (1.05)

0.83 (1.03)

0.90 (1.05)

0.051

Sleep disturbance

1

1.15 (1.16)

1.18 (1.19)

1.14 (1.16)

0.349

Financial impacts

1

1.58 (1.24)

1.79 (1.29)

1.52 (1.22)

< 0.001

  1. Values are presented as mean (standard deviations)
  2. *A higher score indicates a better quality of life
  3. ¶A higher score indicates a higher level of functioning
  4. §A higher score indicates a greater degree of symptoms