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Table 1 Distribution of age, gender and positivity for immunohistochemical biomarkers

From: Clinical impact of panel gene sequencing on therapy of advanced cancers of the digestive system: a retrospective, single center study

 

All

(n = 155)

CRC

(n = 83)

CCC

(n = 29)

EGJ

(n = 15)

PDAC

(n = 13)

HCC

(n = 4)

Others

(n = 11)

Age [yrs]

       

Median (Range)

61 (24–90)

60 (25–90)

63 (38–78)

58 (24–84)

62 (39–82)

58 (49–64)

63 (32–81)

Gender, n [%]

       

Male

98 [63%]

45 [54%]

20 [69%]

13 [87%]

7 [54%]

4 [100%]

9 [82%]

Female

57 [37%]

38 [46%]

9 [31%]

2 [13%]

6 [46%]

0

2 [18%]

Mismatch repair status, n [%]

       

pMMR

121 [78%]

74 [89%]

21 [73%]

13 [87%]

7 [54%]

0

6 [55%]

dMMR

7 [5%]

5 [6%]

1 [3%]

0

0

0

1 [9%]

ND

27 [17%]

4 [5%]

7 [24%]

2 [13%]

6 [46%]

4 [100%]

4 [36%]

Her2-status, n [%]

       

Her2-negative

55 [36%]

22 [27%]

13 [45%]

13 [87%]

3 [23%]

0

4 [36%]

Her2-positive

0

0

0

0

0

0

0

ND

100 [64%]

61 [73%]

16 [55%]

2 [13%]

10 [77%]

4 [100%]

7 [64%]

  1. Abbreviations: CRC Colorectal cancer, CCC Cholangiocellular carcinoma, EGJ Esophagogastric junction adenocarcinoma, PDAC pancreatic ductal adenocarcinoma, HCC Hepatocellular carcinoma, pMMR proficient mismatch repair, dMMR deficient mismatch repair, ND Not determined