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Table 1 Patients characteristics

From: Utility of bronchoscopically obtained frozen cytology pellets for next-generation sequencing

 

Frozen Cytology Pellet (n = 75)

Frozen Tissue (n = 57)

ORR (95%CI)

P value

Age-Median [IQR]

72 [65.5–76]

71 [66–74]

 

0.47

male/female

58/17

43/14

0.9 (0.37–2.21)

0.84

Brinkman Index Median [IQR]

900 [440–1210]

940 [570–1060]

 

0.69

primary tumor size(mm) Median [IQR]

35 [25–46]

50 [35–63]

 

 < 0.01

Stage

   

0.08

 II

3 (4.0%)

9 (15.8%)

  

 III

32 (42.7%)

17 (29.8%)

  

 IV

38 (50.6%)

29 (50.9%)

  

Recurrent

2 (2.7%)

2 (3.5%)

  

Histology

   

0.37

 Adeno

39 (52.0%)

27 (47.4%)

  

 Sq

17 (22.6%)

21 (36.8%)

  

 NOS

9 (12.0%)

4 (7.0%)

  

 SCLC

9 (12.0%)

5 (8.8%)

  

 LCNEC

1 (1.4%)

0

  

Procedure

   

 < 0.01

 EBUS-TBNA

31 (41.3%)

3 (5.3%)

  

 TBB (ultrathin)

1 (1.4%)

1 (1.7%)

  

 EBUS-GS-TBB (thin)

27 (36.0%)

21 (36.8%)

  

 EBUS-GS-TBB (thick)

4 (5.3%)

11 (19.3%)

  

 EBB

10 (13.3%)

18 (31.6%)

  

 TBB under X-ray fluoroscopy

2 (2.7%)

3 (5.3%)

  
  1. Adeno adenocarcinoma, Sq squamous cell carcinoma, NOS not other specified, SCLC small cell carcinoma, LCNEC large cell neuroendocrine carcinoma, EBUS-TBNA endobronchial ultrasound-guided transbronchial needle aspiration, TBB transbronchial biopsy, EBUS-GS-TBB endobronchial ultrasound with a guide sheath transbronchial biopsy, EBB endobronchial biopsy