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Table 3 Univariate and multivariate analyses of variables linked to pCR with ESCC patients

From: A combined nomogram based on radiomics and hematology to predict the pathological complete response of neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma

 

Univariate analysis

Multivariate analysis

Variable

P-value

OR (95%CI)

P-value

OR (95%CI)

Sex

  

-

-

 Female

ref

ref

  

 Male

0.149

0.515(0.209,1.269)

  

Age

  ≤ 60

ref

ref

ref

ref

  > 60

0.040*

2.100(1.035,4.262)

0.395

1.602(0.544,4.886)

cT stage

  

-

-

 2

ref

ref

  

 3

0.393

0.592(0.177,1.973)

  

 4

0.486

0.560(0.105,2.986)

  

cN stage

 0

ref

ref

ref

ref

 1

0.019*

3.850(1.243,11.924)

0.030*

6.014(1.319,34.673)

 2

0.048*

3.500(0.036,341.623)

0.012*

9.857(1.810,67.312)

cTNM stage

  

-

-

 II

ref

ref

  

 III

0.092

2.111(0.886,5.033)

  

 IV

0.509

1.600(0.059,43.564)

  

KPS score

  

-

-

 80

ref

ref

  

 90

0.446

1.320(0.647,2.695)

  

Tumor differentiation

  

-

-

 High

ref

ref

  

 Low

0.358

0.571(0.173,1.886)

  

 Middle

0.297

0.542(0.089,3.279)

  

Tumor location

  

-

-

 Lower

ref

ref

  

 Middle

0.800

1.097(0.535,2.247)

  

 Upper

0.485

0.565(0.118–2.712)

  

Smoking history

  

-

-

 No

ref

ref

  

 Yes

0.881

0.950(0.487,1.853)

  

Drinking history

  

-

-

 No

ref

ref

  

 Yes

0.595

1.200(0.613,2.348)

  

Tumor length

0.032*

0.757(0.587,0.976)

0.028*

0.619(0.395,0.935)

radScore

 < 0.001*

17.674(6.678,46.779)

 < 0.001*

23.555(7.983,92.744)

hemScore

 < 0.001*

5.709(2.853,11.426)

 < 0.001*

7.406(3.090,21.206)

  1. Note. cT clinical T category, cN clinical N category, cTNM clinical TNM category, KPS Karnofsky performance status, * represented statistical significance