Table 1 Outcome measures of primary and secondary endpoints
Endpoints | Questions | Categories in questionnaires | Categories used in analysis |
|---|---|---|---|
Primary | How often during the past month have you had negative thoughts about your prostate/colon/rectal cancer, suddenly and unintentionally? | 1 ‘Never’, 2 ‘More seldom than once a week’, 3 ‘At least once a week’, 4 ‘At least three times a week’, 5 ‘At least once a day’, 6 ‘At least three times a day’ and 7 ‘At least seven times a day’ | 1, 2, 3, 4–7 (combined) |
Co-primary | How intrusive have you experienced the sudden negative thoughts about your prostate/colon/rectal cancer? | 1. ‘Not applicable, I have not had any sudden thoughts about cancer’, 2. ‘Not at all intrusive’, 3. ‘A little bit intrusive’, 4. ‘Moderately intrusive’, 5. ‘Very intrusive’ | 1, 2, 3, 4–5 (combined) |
Secondary 1 | Would you call yourself depressed? | 1. ‘No’, 2. ‘Yes’, 3. ‘I don’t know’ | 1, 2–3 (combined) |
Secondary 2 | How would you describe your quality of life during the past month? | 0 (‘No quality of life’), 1, 2, 3, 4, 5, 6 (‘Best possible quality of life’) | 0–3 (combined), 4, 5, 6 |
Secondary 3 | Have you experienced period of intense anxiety, worry or panic in the last month (for example palpitations, shortness of breath or dizziness)?a | 1 ‘Never’, 2 ‘More seldom than once a week’, 3 ‘At least once a week’, 4 ‘At least three times a week’, 5 ‘At least once a day’, 6 ‘At least three times a day’ and 7 ‘At least seven times a day’ | 1, 2, 3–7 (combined) |