Predictive value of CT and 18F-FDG PET/CT features on spread through air space in lung adenocarcinoma

BMC Cancer

Table 3 Univariable Analysis Results for CT features

Characteristic	All patients	STAS (+)	STAS (-)	t/χ² value	p-value
Tumor location				1.964^a	0.147
Central	9	7	2
Peripheral	99	53	46
Type of nodules				16.233	< 0.001
Solid	58	42	16
Part-solid	39	16	23
GGN	11	2	9
Maximum tumor diameter, cm	2.2 ± 0.9	2.4 ± 0.9	1.9 ± 0.7	3.400	0.001
Maximum solid component diameter, cm	1.7 ± 1.1	2.2 ± 1.0	1.2 ± 1.0	4.990	< 0.001
CTR				22.377	< 0.001
CTR = 1	58	42	16
0.5 ≤ CTR < 1.0	28	15	13
0 ≤ CTR < 0.5	22	3	19
Shape				0.007	0.931
Round to oval	49	27	22
Irregular	59	33	26
Margin				0.347	0.556
Smooth	71	38	33
Blurred	37	22	15
Vascular convergence				2.779	0.095
Present	70	43	27
Absent	38	17	21
Air bronchogram				2.067	0.15
Present	12	9	3
Absent	96	51	45
Pleural indentation				12.188	< 0.001
Present	71	48	23
Absent	37	12	25
Cavitation				1.463^a	0.339
Present	97	52	45
Absent	11	8	3
Lobulation				6.492	0.011
Present	88	54	34
Absent	20	6	14
Spiculation				5.027	0.025
Present	75	47	28
Absent	33	13	20
Ill-defined peripheral opacity				0.697	0.404
Present	43	26	17
Absent	65	34	31

Note: ^aFisher exact test; STAS Spread through air space, STAS ( +)STAS-positive, STAS (-)STAS-negative, CTR consolidation/tumor ratio

ISSN: 1471-2407