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Table 1 Patient demographics and baseline characteristics

From: First-in-human study of GFH018, a small molecule inhibitor of transforming growth factor-β receptor I inhibitor, in patients with advanced solid tumors

 

Total

(N = 50)

Age, y

Median

(Min, max)

52.5

(27, 68)

Sex

Male, n (%)

23 (46.0%)

ECOG, n (%)

0

3 (6.0%)

1

47 (94.0%)

Tumor types

CRC

13 (26.0%)

NSCLC

8 (16.0%)

GC/GEJC

3 (6.0%)

Endometrial cancer

3 (6.0%)

Breast cancer

2 (4.0%)

Others

21 (42.0%)

Prior antitumor

Regimen, n (%)

0

0

1

5 (10.0%)

2

7 (14.0%)

≥ 3

37 (74.0%)

Prior anti-PD-1 therapy

Yes

24 (48.0%)

No

26 (52.0%)

  1. Abbreviations: NSCLC non-small cell lung cancer, GC gastric cancer, GEJC gastroesophageal junction cancer