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Table 3 Univariate and multivariate Cox models evaluated the effect of the depth of PNI on OS and DFS in Stage II CRC patients with PNI

From: The depth of perineural invasion is an independent prognostic factor for stage II colorectal cancer

 

Univariate Cox model

Multivariate Cox model

Hazard Ratio (95% CI)

P-value

Hazard Ratio (95% CI)

P-value

OS: the depth of PNIa

 sup-PNI

    

 deep-PNI

4.688(2.673–8.222)

< 0.001

3.171(1.669–6.025)

< 0.001

DFS: the depth of PNIb

 sup-PNI

    

 deep-PNI

3.181(2.059–4.914)

< 0.001

2.817(1.744–4.549)

< 0.001

  1. aAdjusted for the depth of PNI, CEA, Tumor Location, T4, Differentiation, dMMR, Vascular Invasion
  2. bAdjusted for the depth of PNI, T4, Differentiation, Vascular Invasion
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BMC Cancer

ISSN: 1471-2407

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