Fig. 2

Tumor marker survival curves and microenvironmental changes in patients with pancreatic cancer. (A)Survival curve analysis of tumor markers(CA242 and CA199). (B)Microbial richness based on the Sobs index; (C-D)Index of community richness; (E-F)Index of community diversity. (G)Bubble plot showing differences in abundance of the seven most abundant genus level in the tumor microorganisms. of patients with pancreatic cancer and chronic pancreatitis. (H)Correlation analysis between tumor markers and microorganism, the mean relative abundance of the microbiome in CA242 and CA199 is represented by the color of the spots in the right panel. ^*: P < 0.05;^**: P < 0.01;^***: P < 0.001. (I)Acinetobacter showed a significant positive correlation with CA242. (B-E, G)using an unpaired two-tailed Student’s t test. (F)using a one-tailed Mann-Whitney test