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Table 3 Comparison of epidemiology, pathology, and outcomes among age groups

From: Impact of age on central lymph nodes involvement in papillary thyroid cancer

Variable

Group I ( 20y)

27 ptn

Group II (> 20-40y)

146 ptn

Group III (> 40y)

142 ptn

Significance

Sex

Male

Female

8

19

31

115

42

100

0.24

BMI median (range)

25.1 (17.5–37.5)

31 (19.5–46.7)

34 (20.5–56.9)

< 0.001

MNG association

No

Yes

18

8

85

56

55

84

< 0.001

FNAC (Besthesda)

I

II

III

IV

V

VI

0

0

0

5

10

7

7

3

5

25

65

15

0

9

9

12

64

28

0.003

Operative time median (range)

180 (90–540)

180 (60–600)

180 (60–510)

0.3

Surgery

Ipsilateral central

Bilateral central

Ipsilateral central & lateral

Bilateral central & ipsilateral lateral

Bilateral central & lateral

Ipsilateral central & bilateral lateral

6

5

6

4

5

1

50

22

41

19

11

3

46

20

44

11

14

7

0.54

Tumour size median (range)

2 (0.5-8)

2 (0.4-6)

2.5 (0.2-7)

0.19

Pathologic focality

Unifocal

Multifocal

17

10

76

65

64

70

0.29

Pathologic laterality

Unilateral

Bilateral

20

7

94

47

92

44

0.75

Extrathyroid extension

No

Yes

16

9

81

27

75

47

0.08

Central node harvest median (range)

6 (1–31)

6 (1–23)

5 (1–35)

0.12

Central node status

Negative

Positive

3

24

47

96

58

83

0.009

No of + ve central nodes median (range)

4 (1–17)

3 (1–20)

3 (1–15)

0.27

Lateral node harvest median (range)

24 (3–98)

16 (1–64)

21 (2–73)

0.004

Lateral node status

Negative

Positive

2

15

9

63

9

67

0.99

No of lateral + ve nodes median (range)

8 (2–43)

5 (1–16)

4 (1–24)

0.22

T stage

1

2

3

4

10

10

6

1

59

50

22

5

47

40

41

9

0.14

N stage

0

1

3

24

44

99

47

95

0.07

Postop hypocalcaemia

No

Yes

22

5

117

29

116

26

0.94

Postop nerve affection

No

Yes

25

2

138

8

122

19

0.061

Length of hospital stay median (range)

3 (1–10)

2 (1–20)

2 (1–25)

0.013

Recurrence

No

Yes

25

1

135

8

120

20

0.026

Estimated mean disease-free survival (95%CI)

108.6 (100-117.1)

106.4 (99.9-112.9)

101.8 (89.8-113.8)

0.043