Table 2 MR analysis of the causal relationship between renal cancer and immune cells

Plasma Blast-Plasma Cell %B cell

MR Egger

20

0.90 (0.85–0.96)

4.78 × 10^–3

Weighted median

20

0.96 (0.90–1.02)

1.46 × 10^–1

Inverse variance weighted

20

0.96 (0.92–1.00)

3.65 × 10^–2

Simple mode

20

1.04 (0.94–1.15)

4.81 × 10^–1

Weighted mode

20

0.95 (0.90–1.00)

8.68 × 10^–2

B cell Absolute Count

MR Egger

20

1.09 (1.02–1.16)

1.36 × 10^–2

Weighted median

20

1.03 (0.97–1.09)

3.42 × 10^–1

Inverse variance weighted

20

1.05 (1.01–1.09)

1.19 × 10^–2

Simple mode

20

0.98 (0.88–1.09)

7.19 × 10^–1

Weighted mode

20

1.05 (0.99–1.11)

1.42 × 10^–1

CD20 on transitional B cell

MR Egger

20

1.09 (1.02–1.17)

1.45 × 10^–2

Weighted median

20

1.07 (1.01–1.13)

2.42 × 10^–2

Inverse variance weighted

20

1.06 (1.02–1.10)

4.38 × 10^–3

Simple mode

20

1.08 (1.00–1.18)

7.95 × 10^–2

Weighted mode

20

1.07 (1.02–1.13)

1.40 × 10^–2

CD8 + T cell Absolute Count

MR Egger

20

1.06 (1.00–1.13)

5.90 × 10^–2

Weighted median

20

1.04 (0.99–1.10)

1.23 × 10^–1

Inverse variance weighted

20

1.04 (1.00–1.08)

2.83 × 10^–2

Simple mode

20

1.07 (0.99–1.16)

1.14 × 10^–1

Weighted mode

20

1.05 (1.00–1.11)

7.47 × 10^–2

HVEM on Effector Memory CD8 + T cell

MR Egger

20

0.86 (0.78–0.96)

1.20 × 10^–2

Weighted median

20

0.89 (0.82–0.98)

1.87 × 10^–2

Inverse variance weighted

20

0.94 (0.88–1.00)

4.37 × 10^–2

Simple mode

20

0.87 (0.73–1.04)

1.42 × 10^–1

Weighted mode

20

0.88 (0.81–0.97)

1.41 × 10^–2

Plasmacytoid Dendritic Cell %Dendritic Cell

MR Egger

20

0.91 (0.85–0.97)

9.56 × 10^–3

Weighted median

20

0.94 (0.89–0.99)

1.80 × 10^–2

Inverse variance weighted

20

0.96 (0.92–0.99)

2.08 × 10^–2

Simple mode

20

0.96 (0.87–1.05)

3.39 × 10^–1

Weighted mode

20

0.94 (0.89–0.98)

1.92 × 10^–2