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Table 1 Characteristics of the patients

From: Analysis of related factors for pathological upgrading of cervical biopsy from CIN3 to cancer after conical resection

Clinical Information

Pathological upgrading group (n = 125)

Pathological non-upgrading group (n = 386)

P

Age (years), Mean ± SD

47.68 ± 9.46

52.11 ± 7.02

< 0.001

Gravidity, Median (IQR)

3.00 (2.00 4.00)

3.00 (2.00 4.00)

0.302

Parity, Median (IQR)

2.00 (1.00 2.00)

2.00 (1.00 2.00)

0.252

Menopausal status, n (%)

  

0.011

Yes

48 (38.40)

202 (53.02)

 

No

73 (58.40)

179 (46.98)

 

TCT, n (%)

  

0.001

HSIL

50 (40.00)

223 (57.77)

 

Non-HSIL

33 (26.40)

83 (21.50)

 

Unknown

42 (33.60)

80 (20.73)

 

High-risk HPV infection, n (%)

  

0.011

HPV16/18 positive

32 (25.60)

67 (17.36)

 

Other high-risk types

16 (12.80)

74 (19.17)

 

Not checked

77 (61.60)

235 (60.88)

 

HPV negative, n (%)

0

10 (2.59)

 

Involvement of glandular tissue, n (%)

  

0.083

Yes

82 (69.81)

300 (77.92)

 

No

43 (30.19)

85 (22.08)

 

Clinical symptoms, n (%)

  

< 0.001

Contact bleeding

68 (54.40)

83 (21.50)

 

Abnormal vaginal discharge

12 (9.60)

39 (10.10)

 

Asymptomatic, detected during routine examination

45 (36.00)

264 (68.39)

 

High-density lipoprotein (mmol/L)

1.31 ± 0.29

1.37 ± 0.34

0.002

Albumin (g/L), Median (IQR)

41.10 (39.60 44.30)

41.90 (39.41 44.40)

0.560

Lymphocyte count (109/L), Median (IQR)

1.70 (1.35 2.20)

1.70 (1.40 2.00)

0.183

Monocyte count (109/L), Median (IQR)

0.39 (0.30 0.51)

0.37 (0.30 0.47)

0.305

Neutrophil count (109/L), Median (IQR)

3.50 (2.90 4.50)

3.10 (2.40 4.00)

0.001

Eosinophil count (109/L), Median (IQR)

0.10 (0.06 0.17)

0.09 (0.06 0.15)

0.254

Red blood cell count (1012/L)

4.01 ± 0.43

3.97 ± 0.47

0.002

Hemoglobin (g/L), Median (IQR)

121.00 (109.00 127.00)

118.50 (112.00 126.00)

0.881

Hematocrit (%), Median (IQR)

36.10 (32.95 38.20)

36.00 (34.10 38.10)

0.567

Red cell distribution width, Median (IQR)

42.90 (40.70 46.55)

43.70 (41.58 46.23)

0.089

Platelet count (109/L), Mean ± SD

204.84 ± 61.24

187.06 ± 73.66

0.012

Mean platelet volume (fl.), Median (IQR)

11.50 (10.60 12.30)

11.90 (11.00 12.90)

0.002

Fibrinogen (g/L), Median (IQR)

2.73 (2.32 3.11)

2.73 (2.39 3.06)

0.842

  1. TCT: ThinPrep Cytology Test; HSIL: high-grade squamous intraepithelial lesion; HPV: human papillomavirus