Table 5 Interaction effect of EPPK1 and stage in a multivariable Cox regression model adjusted for gender and pack year for each histology
From: Elucidating the role of EPPK1 in lung adenocarcinoma development
Histology | Variable | Coef | exp(Coef) | se(Coef) | z | P value |
|---|---|---|---|---|---|---|
LUAD | Pack Years | 0.01 | 1.01 | 0.01 | 1.21 | 0.22 |
Gender (Male vs. Female) | 0.94 | 2.57 | 0.3 | 3.12 | < 0.01 | |
EPPK1 (High expression vs. Low expression) | 0.41 | 1.51 | 0.34 | 1.21 | 0.22 | |
Stage (III + IV vs. I + II) | 1.61 | 5.01 | 0.42 | 3.8 | < 0.01 | |
EPPK1 x Stage | -2.43 | 0.09 | 0.7 | -3.48 | < 0.01 | |
LUSC | Pack Years | -0.01 | 0.99 | 0 | -2.1 | 0.04 |
Gender (Male vs. Female) | -0.03 | 0.97 | 0.23 | -0.13 | 0.89 | |
EPPK1 (High expression vs. Low expression) | 0.14 | 1.15 | 0.37 | 0.39 | 0.7 | |
Stage (III + IV vs. I + II) | 0.87 | 2.39 | 0.33 | 2.66 | 0.01 | |
EPPK1 x Stage | 0.02 | 1.02 | 0.43 | 0.04 | 0.96 |