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Fig. 2 | BMC Cancer

Fig. 2

From: Eukaryotic initiation factor 3a promotes the development of diffuse large B-cell lymphoma through regulating cell proliferation

Fig. 2

eIF3a promoted the growth of DLBCL cells. (A) Relative expression of eIF3a mRNA was confirmed by qRT-PCR. (B, C) DLBCL cells transfected with SI-LV displayed significantly decreased expression of eIF3a protein than those transfected with NC-LV. (D) Cell proliferation was evaluated by CCK8 assays. The proliferation efficiency of DLBCL cells was markedly decreased in DLBCL cells with eIF3a knock down. (E, F) Knockdown of eIF3a reduced the expression of proliferation-related proteins. The results of triplicate experiments were shown as the mean ± SD. **P < 0.01, *** P < 0.001, **** P < 0.0001

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