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Fig. 1 | BMC Cancer

Fig. 1

From: Eukaryotic initiation factor 3a promotes the development of diffuse large B-cell lymphoma through regulating cell proliferation

Fig. 1

The expression of eIF3a was upregulated in DLBCL and correlated with worse prognosis. (A) The expression levels of eIF3a in DLBCL and healthy control groups from GSE25638. (B) Kaplan-Meier curves for OS of DLBCL patients with high- or low- expressed eIF3a levels in GSE31312 (P = 0.0063). (C, D) The expression levels of eIF3a protein in DLBCL cell lines (LY1, LY3, LY8 and U2932) and PBMCs from healthy donors. The results of triplicate experiments were shown as the mean ± SD. (E, F) Compared with RHL, the expression level of eIF3a was significantly increased in DLBCL tissues. Original magnification, ×100 and ×400. (G) Kaplan-Meier survival analysis showed shorter OS in patients with positive expression of eIF3a. **P < 0.01, *** P < 0.001, **** P < 0.0001

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BMC Cancer

ISSN: 1471-2407

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