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Table 3 Organ at risk constraints for the experimental arm

From: SABR-Dual: a phase II/III trial of two-fraction versus five-fraction stereotactic radiotherapy for localized low- and favorable intermediate-risk prostate cancer

Structure

Parameter (Gy)

Per protocol

Variation acceptable

Bladder

D0.03 cc

< 28.08 Gy

D0.5cc < 27.54 Gy

V16.2

≤ 25%

 

V16.2

≤ 50 cc

 

Rectum

D0.03 cc

< 27 Gy

 

D1cc

< 22.95 Gy

D2cc < 21.6 Gy

V23

≤ 10%

 

V19

≤ 20%

 

V10

≤ 50%

 

Rectal wall

(any slice)

35% circumf.

< 20 Gy

Semi-quantitative visualization

50% circumf.

< 13.5 Gy

UrethraPRV

D0.03 cc

< 27.54 Gy

 

Urethra

D0.03 cc

≤ 27 Gy

 

Femoral head

V13.5

≤ 10 cc

 

V13.5

≤ 5%

 

Penile bulb

D0.03 cc

< 24.3 Gy

 

V13.5

≤ 30%

 

Crura

Dmean

< 3.78 Gy

 

D2%

< 8.8 Gy

 

Skin

D0.03 cc

< 13.5 Gy