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Table 2 Organ at risk constraints for the standard arm

From: SABR-Dual: a phase II/III trial of two-fraction versus five-fraction stereotactic radiotherapy for localized low- and favorable intermediate-risk prostate cancer

Structure

Parameter (Gy)

Per protocol

Variation acceptable

Bladder

D0.03 cc

< 42 Gy

D0.5cc < 41.2 Gy

V26

≤ 25%

 

V26

≤ 50 cc

 

Rectum

D0.03 cc

< 40.8 Gy

 

D1cc

< 38.5 Gy

D2cc < 38 Gy

V36

≤ 10%

 

V32

≤ 20%

 

V20

≤ 50%

 

Rectal wall (any slice)

35% circumf.

< 39 Gy

Semi-quantitative visualization

50% circumf.

< 24 Gy

UrethraPRV

D0.03 cc

< 40.8 Gy

 

Urethra

D0.03 cc

≤ 40 Gy

 

Femoral head

V22

≤ 10 cc

 

V22

≤ 5%

 

Penile bulb

D0.03 cc

< 38 Gy

 

V22

≤ 30%

 

Crura

Dmean

< 4.7 Gy

 

D2%

< 12 Gy

 

Skin

D0.03 cc

< 25 Gy