Stereotactic ablative brachytherapy versus percutaneous microwave ablation as salvage treatments for lung oligometastasis from colorectal cancer

Table 3 Cox regression analysis of the entire cohort

	Univariable Cox regression		Multivariable Cox regression
	HR (95% CI)	P	HR (95% CI)	P
LTPFS Sex
Female
Male	0.359 (0.153–1.098)	0.146
Age (years)
<65
≥65	0.684 (0.327–1.753)	0.618
Treatment of lung metastasis
L-SABT
MWA	0.349 (0.103–0.568)	0.083
Tumor diameter
≤3 cm
>3 cm	0.925 (0.258–3.094)	0.025	1.437 (0.893–3.594)	0.021
Distribution of lung metastasis
Unilateral
Bilateral	2.357 (0.961–5.336)	0.257
Distance from hilum pleura/interlobar fissure
≤10 mm
>10 mm	3.453 (1.568–8.752)	0.056	3.132 (1.083–6.547)	0.097
Lung metastasis
Metachronous
Synchronous	3.104 (1.476–5.331)	0.037	1.673 (0.937–3.961)	0.298
CEA(ng/ml)
<10
≥ 10	2.802 (1.531–5.126)	0.001	2.346 (1.240–4.436)	0.017
OS
Sex Female Male	0.356 (0.189–1.235)	0.097	0.641 (0.235–1.672)	0.253
Age (years) < 65 ≥ 65	0.757 (0.368–1.696)	0.492
Treatment of lung metastasis
L-SABT
MWA	0.472 (0.225–1.428)	0.163
Tumor diameter
≤3 cm
>3 cm	1.576 (0.446–4.684)	0.095	1.987 (1.068–3.722)	0.036
Distribution of lung metastasis
Unilateral
Bilateral	1.779 (0.432–4.775)	0.229
Distance from hilum/pleura/interlobar fissure
≤10 mm
>10 mm	2.984 (1.097–6.403)	0.087	2.531 (0.924–5.773)	0.151
Lung metastasis
Metachronous
Synchronous	2.577 (1.458–4.669)	0.062	1.332 (0.859–3.452)	0.338
CEA (ng/ml)
<10
≥10	2.996 (1.345–5.667)	0.004	2.698 (1.042–4.337)	0.013

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