Table 1 Participant demographics and baseline characteristics
| Â | Doublet Arms | Triplet Arms | ||||
|---|---|---|---|---|---|---|
|  | Arm 1A (n = 10) | Arm 2A (n = 27) | Pooled (n = 37) | Arm 1B (n = 11) | Arm 2B (n = 27) | Pooled (n = 38) |
Age at screening, years | ||||||
 Mean (SD) | 62.6 (9.17) | 57.8 (11.80) | 59.1 (11.24) | 56.5 (10.02) | 57.8 (12.07) | 57.4 (11.39) |
 Median (min, max) | 63.5 (44, 74) | 59.0 (31, 80) | 60.0 (31, 80) | 59.0 (41, 71) | 61.0 (29, 78) | 59.5 (29, 78) |
Age group at screening, n (%) | ||||||
  < 65 years | 5 (50.0) | 19 (70.4) | 24 (64.9) | 9 (81.8) | 20 (74.1) | 29 (76.3) |
  ≥ 65 years | 5 (50.0) | 8 (29.6) | 13 (35.1) | 2 (18.2) | 7 (25.9) | 9 (23.7) |
Sex, n (%) | ||||||
 Male | 8 (80.0) | 16 (59.3) | 24 (64.9) | 7 (63.6) | 17 (63.0) | 24 (63.2) |
 Female | 2 (20.0) | 11 (40.7) | 13 (35.1) | 4 (36.4) | 10 (37.0) | 14 (36.8) |
Race, n (%) | ||||||
 White | 9 (90.0) | 21 (77.8) | 30 (81.1) | 11 (100) | 23 (85.2) | 34 (89.5) |
 Black or African American | 1 (10.0) | 1 (3.7) | 2 (5.4) | 0 | 1 (3.7) | 1 (2.6) |
 Asian | 0 | 1 (3.7) | 1 (2.7) | 0 | 0 | 0 |
 Other | 0 | 4 (14.8) | 4 (10.8) | 0 | 3 (11.1) | 3 (7.9) |
Ethnicity, n (%) | ||||||
 Hispanic/Latino | 0 | 1 (3.7) | 1 (2.7) | 0 | 0 | 0 |
 Not Hispanic/Latino | 10 (100) | 21 (77.8) | 31 (83.8) | 11 (100) | 23 (85.2) | 34 (89.5) |
 Unknown | 0 | 1 (3.7) | 1 (2.7) | 0 | 0 | 0 |
 Not reported | 0 | 4 (14.8) | 4 (10.8) | 0 | 4 (14.8) | 4 (10.5) |
ECOG PS n (%) | ||||||
 0 | 7 (70.0) | 13 (48.1) | 20 (54.1) | 3 (27.3) | 11 (40.7) | 14 (36.8) |
 1 | 3 (30.0) | 14 (51.9) | 17 (45.9) | 8 (72.7) | 16 (59.3) | 24 (63.2) |