Fig. 7

Example of stereotactic biopsy within a habitat of the posterior thigh. (A) MRI identification of Habitat 1 (blue) target. To account for sofit tissue rotation, needle insertion is designated at the proximal tattoo (BB#1) and a depth of 7 cm towards the center of the femur is measured, with a medial tangential 5.5 cm line (90 degrees), creating the final biopsy track 9 cm from the surface. (B) CT measurements, biopsy, and clip placement are illustrated. Each site is defined by a different marker (e.g., one visicoil proximal biopsy, two visicoils at midpoint habitat, and one visicoil plus one helical mammotome for the distal habitat sampled). In addition to helping with daily set up, these markers will also be used at the time of pathological evaluation to orient the specimen and determine treatment response within each habitat