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Fig. 5 | BMC Cancer

Fig. 5

From: Characterization of tumoricidal activities mediated by a novel immune cell regimen composing interferon-producing killer dendritic cells and tumor-specific cytotoxic T lymphocytes

Fig. 5

AIM+ CD8 T cells exhibited T cell-dependent cytotoxicity against primary epithelial OC. (a, b) OC cells were cocultured with T cells, and the TFL-4+caspase/granzyme B+ pattern was analyzed through flow cytometry to quantify apoptosis. c The correlation between T cell-dependent cytotoxicity and the percentage of 4-1BB+IFN-γ+, 4-1BB+perforin+and 4-1BB+CD107a+on CD8 T cells was determined. The results shown in (a) are representative of six independent experiments. Data are presented as means ± SD of six independent experiments. Differences between groups were analyzed using the nonparametric Mann-Whitney test. p values:*p < 0.05

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BMC Cancer

ISSN: 1471-2407

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