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Fig. 3 | BMC Cancer

Fig. 3

From: Exploring the relationship between Treg-mediated risk in COPD and lung cancer through Mendelian randomization analysis and scRNA-seq data integration

Fig. 3

Single-cell sequencing reveals the dynamic changes of CD4 + T cells and CD8 + T cells in COPD and lung cancer. (A) UMAP plot showing the subtypes of T cells, including CD4 + T cells and CD8 + T cells. (B and C) The expression pattern of CD4 and CD8A markers in T cell subpopulations. (D) Stacked barplot comparing the relative frequencies of CD4 + T cells and CD8 + T cells among COPD, lung cancer and normal samples. (E and F) Boxplots showing the distribution of frequencies for CD4 + T cells and CD8 + T cells across different sample groups

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