Table 4 Incidence of significant genitourinary and gastrointestinal toxicities in patients receiving prostate radiotherapy
Toxicity | Fractionation type | P-value | |
|---|---|---|---|
Conventional n = 14 (41.2%) | Hypofractionation n = 20 (58.8%) | ||
Acute GU toxicity G2+ | 12 (85.7%) | 19 (95%) | 0.555 f |
Cystitis, bladder spasm G2 | 9 (75%) | 11 (57.9%) | 0.452 f |
G3+ | 3 (25%) | 8 (42.1%) | |
Hematuria G2 | 6 (66.7%) | (46.7%) | 0.423 f |
G3+ | 3 (33.3%) | 8 (53.3%) | |
Obstruction G2 | 0 (0%) | (12.5%) | 1.000 f |
G3+ | 4 (100%) | 7 (87.5%) | |
Acute GI toxicity G2+ | 7 (50%) | 9 (45%) | 0.774 |
Diarrhea G2 | 3 (100%) | 0.100 f | |
G3+ | 3 (100%) | ||
GI upset G2 | 4 (100%) | 1 (25%) | 0.143 f |
G3+ | 3 (75%) | ||
Proctitis, Abdominal pain G2 | 6 (85.7%) | 5 (55.6%) | 0.308 f |
G3+ | 1 (14.3%) | 4 (44.4%) | |
Fissure/ fistula G3+ | 2 (14.3%) | 1 (5%) | 0.555 f |
Rectal bleeding G3+ | 2 (14.3%) | 1 (5%) | 0.555 f |
Late GU toxicity G2+ | 2 (16.7%) | 3 (17.6%) | 1.000 f |
Cystitis, bladder spasm G2 | 1 (33.3%) | 1 (33.3%) | 1.000 f |
G3+ | 2 (66.7%) | 2 (66.7%) | |
Hematuria G2 | 1 (33.3%) | 1.000 f | |
G3+ | 2 (100%) | 2 (66.7%) | |
Obstruction G3+ | (16.7%) | 2 (11.8%) | 1.000 f |
Erectile dysfunction | 11 (100%) | 17 (100%) | |
Late GI toxicity G2+ | 1 (9.1%) | 1(5.9%) | 1.000 f |
Proctitis, Abdominal pain G2 | 1 (100%) | 1.000 f | |
G3+ | 1 (100%) | ||
Fissure/ fistula G3+ | 1 (9.1%) | 0.393 f | |