Table 3 Bivariate and multivariate analysis for predictors of overall survival
Predictor variables | Categories | CrudeHazard Ratio (95% C.I) | p-value | AdjustedHazard Ratio (95% C.I) | p-value |
|---|---|---|---|---|---|
Age | < 5 years | 1 | 1 | ||
≥ 5 years | 1.50 (0.52–4.34) | 0.452 | 0.539 (0.10–2.78) | 0.461 | |
Sex | Male | 1 | 1 | ||
Female | 1.59 (0.53–4.77) | 0.404 | 1.234 (0.26–5.71) | 0.788 | |
Wilms tumor stage | Stage 3 | 1 | 1 | ||
Stage 4 | 2.366 (0.72–7.70) | 0.152 | 3.312 (0.77–14.21) | 0.107 | |
Histology type | Favorable | 1 | 1 | ||
Unfavorable | 5.16 (1.79–14.89) | 0.002 | 73.836(8.13–669.83) | 0.000* | |
Treatment response | No relapse | 1 | 1 | ||
Relapse | 1.46 (0.50–4.22) | 0.481 | 1.164 (0.25–5.34) | 0.844 | |
Surgery | Nephrectomy done | 1 | 1 | ||
Nephrectomy not done | 1.763 (0.22–13.55) | 0.586 | 0.152 (0.005–4.01) | 0.260 | |
Compliance to chemotherapy | Received on schedule | 1 | 1 | ||
Not received on schedule | 0.646 (0.21–193) | 0.435 | 0.351 (0.06–1.98) | 0.236 | |
Tumor size | ≤ 15 cm | 1 | 1 | ||
> 15 cm | 1.44 (0.50–4.16) | 0.495 | 5.87 (1.04–33.03) | 0.044* |