Fig. 1

Survival analysis of LUAD cases and comparison of gene somatic mutation rates between different prognosis groups. a. Overall survival of LUAD cases. The median survival time was indicated with red dashes. b. The survived and dead LUAD cases within 1, 3 and 5 years. c. The number of genes with significant mutation rate difference between good and poor prognosis groups at different significance levels. The genes with higher mutation rates in good and poor prognosis groups were shown in red and grey, respectively. d. Gene Ontology (GO) biological process enrichment of genes with significant mutation rates between prognosis groups at EBT p value < 0.15 and 0.20, respectively. The significantly enriched function clusters were shown in orange background (cell-cell adhesion) or in red (cell motility), respectively (Fisher’s Exact with FDR multiple test correction)