Radiomics based analysis to predict local control and survival in hepatocellular carcinoma patients treated with volumetric modulated arc therapy

Table 5 Significant covariates with respect to the survival and related log-rank test P-Values

Covariate	p-Value	HR	95%CI
Total Dose	0.01	0.08	0.01–0.63
Localization of tumour	0.04	0.26	0.06–1.10
PV thrombosis	<0.001	3.51	2.01–6.13
AJCC Stage	0.001	1.42	1.10–3.01
BCLC Stage	<0.001	1.38	0.95–2.84
Child Class	0.04	1.63	1.02–2.61
AFP initial level	<0.001	0.39	0.25–0.63
Tumour volume	<0.001	0.25	0.16–0.40
Age	0.006	2.02	1.20–3.39
Entropy (Histogram)	0.02	1.70	1.09–2.67
Compacity	<0.001	0.22	0.14–0.36
Contrast	0.01	2.11	1.14–4.12
Entropy	0.04	1.61	1.03–2.88
Dissimilarity	0.01	2.17	1.14–4.12
HGRE	0.02	1.80	1.07–3.01
SRHGE	0.02	1.69	1.06–2.67
LRHGE	0.04	1.71	1.02–2.88
GLNU	<0.001	0.23	0.13–0.39
RLNU	<0.001	0.25	0.16–0.40
HGZE	0.02	1.83	1.09–3.07
SZHGE	0.01	1.80	1.12–2.87
GLNU	<0.001	0.25	0.15–0.39

Continuous numerical covariates have been split into two categories for calculating statistical test

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