Fig. 5
From: CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer
ALKBH3 promoter methylation with respect to clinical parameters and breast cancer-specific survival. a ALKBH3 promoter methylation analysed with respect to clinical and subtype-specific markers: estrogen-receptor, progesterone-receptor, HER-2 over-expression and Ki-67. The P-values shown were derived from Wilcoxon’s hypothesis testing. b ALKBH3 promoter methylation analysed with respect to patient survival (breast cancer-specific survival). The analyses shown were carried out using increasingly higher threshold levels for ALKBH3 promoter methylation as indicated. The P-values were derived from log-rank hypothesis testing for differences in survival outcomes