Fig. 5From: Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathwaysWestern blot analyses with cells treated with metformin and/or nutlin-3a. Cells were treated with metformin, nutlin-3a, DMSO as a solvent control, or metformin pulse nutlin-3a at the indicated concentrations for 24 and 48 h. Cell lysates were probed with antibody as indicated. GAPDH was used as a loading controlBack to article page