Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis

Table 1 Characteristics of included randomized trials

Trial(year)	Time	Country	Intervention	n-3 PUFA,n	Contro l, n	Age	BMI	Cancer	Studu design	Parameters
Ma et al. [12]	2015	China	0.8–1.5 g/kg/d LCT,MCT, n-3PUFA	44	41	61.55 ± 9.78	23.45 ± 3.44 44	stomach, colon	Randomized	IL-6, CRP, TNF-α
Ziran et al. [13]	2014	Brazil	104–125 kJ/kg/d EPA + DHA	26	20	36–74	17.8–29.7	stomach	Randomized	CD3, CD4, CD8, CD4/CD8, albumin, L-6, CRP, TNF-α
Liu et al. [14]	2009	China	83.68 kJ/kg/d n-3PUFA	22	20	64.02	Not Given	stomach, colon	Randomized	CD3, CD4, CD8, CD4/CD8, albumin, CRP
Hu et al. [15]	2015	China	104–125 kJ/kg/d n-3PUFA	44	44	23–78	Not Given	stomach, colon	Randomized	CD3, CD4, CD8, CD4/CD8, IL-6, CRP, TNF-α
Zheng et al. [16]	2011	China	25 kcal//kg/d n-3PUFA	20	20	56.19 ± 11.80	Not Given	colon, rectum	Randomized	CD3, CD4, CD4/CD8, albumin, CRP
ZHU et al. [17]	2012	China	1.2 g/kg/d n-3PUFA	29	28	70.8 ± 6.4	18.5–25.0	colon	Randomized	CD4, CD8, CD4/CD8, IL-6, TNF-α
Aoife et al. [18]	2009	Ireland	2.2 g/d EPA	28	25	62	24.6	esophagus	Randomized	albumin, IL-6
Huang et al. [19]	2014	China	25 kcal//kg/d n-3PUFA	40	40	60.88 ± 7.54	Not Given	esophagus	Randomized	CD3, CD4, CD8, CD4/CD8
Sultan et al. [20]	2012	UK	EPA 0·51 g/100 ml + DHA 0·22 g /100 ml	66	66	67 (42–79)	Not Given	esophagus, stomach	Randomized	CD3, CD4, CD8, CD4/CD8

ISSN: 1471-2407