Table 6 Univariate and multivariate survival analyses of stage ypIII RC patients who received Pre-RT
Characteristic | 5-year CCS | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
χ2 test | P | HR(95%CI) | P | ||
Year of diagnosis | 0.038 | 0.846 | NI | ||
2004–2007 | 65.6% | ||||
2008–2010 | 67.0% | ||||
Sex | 0.026 | 0.872 | NI | ||
Male | 65.9% | ||||
Female | 66.2% | ||||
Age | 17.245 | 0.000 | 0.000 | ||
< 60 | 69.3% | Ref | |||
≥ 60 | 60.9% | 0.747 (0.654 ~ 0.866) | 0.000 | ||
Race | 17.535 | 0.000 | 0.625 | ||
White | 66.8% | Ref | |||
Black | 51.6% | 1.125 (0.880 ~ 1.436) | 0.347 | ||
Others | 71.3% | 1.767 (1.290 ~ 2.421) | 0.000 | ||
Grade | 41.722 | 0.000 | 0.000 | ||
Grade I/ II | 69.5% | Ref | |||
Grade III/ IV | 53.9% | 0.670 (0.566 ~ 0.794) | 0.000 | ||
Histologic type | 24.617 | 0.000 | 0.037 | ||
Adenocarcinoma | 67.4% | Ref | |||
Mucinous adenocarcinoma | 60.7% | 0.562 (0.378 ~ 0.836) | 0.004 | ||
Signet ring cell carcinoma | 41.8% | 0.588 (0.383 ~ 0.904) | 0.016 | ||
ypT stage | 66.241 | 0.000 | 0.000 | ||
1 | 73.0% | Ref | |||
2 | 83.7% | 0.442 (0.242 ~ 0.810) | 0.008 | ||
3 | 65.1% | 0.276 (0.195 ~ 0.391) | 0.000 | ||
4 | 46.8% | 0.564 (0.451 ~ 0.704) | 0.000 | ||
LNs | 1.975 | 0.160 | NI | ||
≤ 12 | 64.9% | ||||
> 12 | 67.0% | ||||
NLN | 33.138 | 0.000 | 0.000 | ||
≤ 9 | 60.5% | Ref | |||
> 9 | 71.4% | 1.466 (1.264 ~ 1.700) | 0.000 | ||