Fig. 1

Serum concentrations of mesothelin (a) and midkine (b) in various diseases. Pleural diseases other than mesothelioma (shown in Table 2) are not included. Box plot with maximum and minimum values and the cut-off values (dotted line, mesothelin: 1.5 nmol/L, midkine; 421 pg/mL) are indicated. Statistical analysis was conducted with Kruskal Wallis tests