Fig. 6
From: u-PAR expression in cancer associated fibroblast: new acquisitions in multiple myeloma progression
a Proliferation assay of U266 myeloma cells enumerated at 24, 48, 72, and 96 h of culture in normal medium (CTR) or in conditioned medium (CM) from sMM untreated, DOTAP-, aODN-, and dODN-treated CAF. Western blot image shows the expression of the proliferation cell nuclear antigen (PCNA) in U266 cells at 96 h of incubation in the above conditions. b Graph depicting the quantification of U266 cells migrated under the stimulus of normal medium (CTR) or medium conditioned by sMM untreated, DOTAP-, aODN-, and dODN-treated CAF (*p < 0.05). Representative optical microscopy images for each culture condition of the invasion assay