Fig. 1
From: Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway
Adipose tissue remodeling is triggered during cancer cachexia. a Haematoxilin and eosin sections of subcutaneous adipose tissue. b Collagen detection by Picro Sirius Red staining. c Localization of elastic fibers performed with Verhoeff’s Van Gieson staining. Photomicrographs of the representative images from each group: Control (n = 5), Weight-stable cancer (WSC; n = 5), Cancer cachexia (CC; n = 5). Ad- Illustrates preserved adipocytes. Arrows indicate intense labeling. F- Indicates areas with excessive ECM deposition (fibrotic areas)