Fig. 2

Immune responsiveness of woodchucks with low viral loads following a single IV dose of JVRS-100. Fold increase in mRNA expression of cytokines and T cell surface markers in peripheral blood following a single IV dose of JVRS-100 at a concentration of 100 μg/animal into woodchucks with low serum WHV DNA load (n = 4). Results are presented as a change from the transcription level observed in control woodchucks with comparable low viral load following a single IV dose of placebo (n = 4). Vertical lines denote standard deviations