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Table 2 Five-year survival (%) and hazard ratios (HR) by level treatment at PTC and diagnostic group

From: Access to principal treatment centres and survival rates for children and young people with cancer in Yorkshire, UK

  

5 year survival

Unadjusted

Adjusteda

Diagnostic group

Level of treatment at PTC

% Survival

95% CI

HR

95%CI

HR

95%CI

Leukaemia

All

81

(78, 84)

1

-

1

-

 

Some

57

(44, 68)

2.34

(1.54, 3.56)

1.61

(0.97, 2.67)

 

None

56

(41, 69)

2.66

(1.68, 4.20)

1.73

(0.98, 3.04)

Lymphoma

All

89

(85, 92)

1

-

1

-

 

Some

84

(74, 90)

1.45

(0.84, 2.51)

1.51

(0.78, 2.92)

 

None

89

(82, 93)

0.98

(0.56, 1.70)

1.12

(0.54, 2.35)

CNS tumours

All

71

(67, 75)

1

-

1

-

 

Some

76

(52, 89)

0.6

(0.25, 1.48)

0.48

(0.19, 1.20)

 

None

72

(55, 84)

0.98

(0.54, 1.75)

0.66

(0.34, 1.29)

Germ cell tumours

All

91

(85, 95)

1

-

1

-

 

Some

94

(88, 97)

0.76

(0.34, 1.70)

1.24

(0.42, 3.65)

 

None

95

(88, 98)

0.62

(0.22, 1.17)

1.83

(0.50, 6.76)

Soft tissue sarcomas

All

54

(45, 63)

1

-

1

-

 

Some & None

75

(59, 85)

0.44

(0.23, 0.83)

0.48

(0.23, 0.99)

Bone tumours

All

56

(47, 64)

1

-

1

-

 

Some & None

60

(36, 78)

0.98

(0.49, 1.97)

0.91

(0.43, 1.88)

  1. Footnote: aAdjusted models from multiple imputation models. Models adjusted for the following
  2. Leukaemia – Diagnostic subgroup, white cell count, age, treatment, relapse, sex, diagnosis year, ethnicity and Townsend area deprivation
  3. Lymphoma – Diagnostic subgroup, stage, age, treatment, relapse, sex, diagnosis year, ethnicity and Townsend area deprivation
  4. CNS tumours – Diagnostic subgroup, grade, age, treatment, relapse, sex, diagnosis year, ethnicity and Townsend area deprivation
  5. Germ cell tumours – Diagnostic subgroup, stage, age, relapse, sex, diagnosis year, ethnicity and Townsend area deprivation (not adjusted for treatment due to collinearity)
  6. Soft tissue sarcomas – Diagnostic subgroup, age, treatment, relapse, sex, diagnosis year, ethnicity and Townsend area deprivation
  7. Bone tumours – Diagnostic subgroup, primary site, age, treatment, relapse, sex, diagnosis year, ethnicity and Townsend area deprivation
  8. Level of treatment at PTC “Some” ranges from 20% to 85% of all treatments received at PTC
  9. Abbreviations: PTC = Principal Treatment Centre, HR = hazard ratio, CI = confidence interval, CNS = Central nervous system