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Table 2 Clinicopathological variables of patients according to the cutoff value of CRP/Alb ratio

From: The C-reactive protein/albumin ratio, a validated prognostic score, predicts outcome of surgical renal cell carcinoma patients

Characteristics

CRP/Alb < 0.08

(n = 393)

CRP/Alb ≥ 0.08

(n = 177)

P value

Age (years)

48.71 ± 12.98

55.25 ± 13.92

<0.001a

BMI

23.65 ± 3.37

23.41 ± 4.02

0.290a

Gender

  

0.219b

 Male

257 (65.40%)

125 (70.60%)

 

 Female

136 (34.60%)

52 (29.40%)

 

Pathological types

  

0.315b

 Clear cell carcinoma

308 (81.20%)

43 (80.80%)

 

 Papillary carcinoma

26 (3.80%)

15 (8.50%)

 

 Others

59 (15.00%)

19 (10.70%)

 

Fuhrman-grade

  

<0.001b

 I

92 (23.40%)

27(15.30%)

 

 II

178(45.30%)

71(40.10%)

 

 III

31(7.90%)

29(16.40%)

 

 IV

2(0.50%)

5(2.80%)

 

 Unknown

90(22.90%)

45(25.40%)

 

pTNM stage

  

<0.001b

 I

313(79.60%)

84(47.50%)

 

 II

53(13.50%)

32(18.10%)

 

 III

22(5.60%)

37(20.90%)

 

 IV

5 (1.30%)

24(13.60%)

 

pT status

  

<0.001b

 T1

318 (80.90%)

89 (50.30%)

 

 T2

54 (13.70%)

40 (22.60%)

 

 T3+ T4

21 (5.30%)

48 (27.10%)

 

pN status

  

<0.001b

 N0

382 (97.20%)

153 (86.40%)

 

 N1

11 (2.80%)

24 (13.60%)

 

pM status

  

<0.001b

 M0

390 (99.20%)

160 (90.40%)

 

 M1

3 (0.80%)

17 (9.60%)

 

Urine protein

  

0.188b

 No

319 (81.20%)

141 (79.7%)

 

 Yes

15 (3.80%)

13 (7.3%)

 

 Unknown

59 (15.00%)

23 (13.00%)

 

ALP

  

0.018b

 Normal

369 (93.90%)

156 (88.10%)

 

 Elevated

24 (6.10%)

21 (11.90%)

 

LDH

  

0.004b

 Normal

335 (85.20%)

133 (75.10%)

 

 Elevated

58 (14.80%)

44 (24.90%)

 

CRE

  

0.001b

 Normal

384 (97.70%)

162 (91.50%)

 

 Elevated

9 (2.30%)

15 (8.50%)

 

UA

  

0.468b

 Normal

321 (81.70%)

140 (79.10%)

 

 Elevated

72 (18.30%)

37 (20.90%)

 

Total protein

  

0.144b

 Normal

352 (89.60%)

151 (85.30%)

 

 Elevated

41 (10.40%)

26 (14.70%)

 

Serum globulin

   

 Normal

273 (69.50%)

87 (49.20%)

<0.001b

 Elevated

120 (30.50%)

90 (50.80%)

 

NLR

  

<0.001b

 < 1.85

205 (52.20%)

37 (20.90%)

 

  ≥ 1.85

188 (47.80%)

140 (79.10%)

 

PLR

  

<0.001b

 < 153

324 (82.40%)

94 (53.10%)

 

  ≥ 153

69 (17.60%)

83 (46.90%)

 
  1. Abbreviation: BMI body mass index, pTNM pathologic tumor–node–metastasis, ALP alkaline phosphatase, LDH lactate dehydrogenase, CRE serum creatinine, UA uric acid, LDH lactate dehydrogenase, NLR neutrophil count to lymphocyte count, PLR platelet count to lymphocyte count, CRP/Alb the serum CRP level to the serum Alb level
  2. aKruskal-Wallis test
  3. bChi-square test