Fig. 1From: Enhanced and long term immunogenicity of a Her-2/neu multi-epitope vaccine conjugated to the carrier CRM197 in conjunction with the adjuvant MontanideExperimental design. Female Balb/C mice were immunized with different amounts of P467 and P647 hybrid peptides, conjugated to either CRM or virosomes (1a; Experiment-I), or with different amounts of P467-CRM administered together with Alum or Montanide (1b; Experiment-II). For examining the kinetic of the immune responses, additional blood samples were taken in two months intervals for the period of 6Â months after the last immunization. The occasions for immunization (black arrows) and bleeding (grey arrows) are indicatedBack to article page