Table 2 MDM2 del1518 among SNP309TT
From: MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
Cases/controls | Genotype del1518 n (%) | OR (95% CI) del1518 | Fisher exact | OR (95% CI) del1518 | Fisher exact | ||
|---|---|---|---|---|---|---|---|
ins/ins | ins/del | del/del | Dominant modela | Recessive modelb | |||
Healthy Controls | 70 (9.5) | 311 (42.0) | 359 (48.5) | 1.00 | - | 1.00 | |
Ovarian cancer | 64 (11.6) | 242 (44.0) | 245 (44.5) | 0.80 (0.56–1.14) | 0.231 | 0.85 (0.68–1.06) | 0.159 |
Endometrial cancer | 81 (14.1) | 247 (42.9) | 248 (43.1) | 0.64 (0.45–0.90) | 0.011 | 0.80 (0.65–1.00) | 0.051 |