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Table 2 Summary of independent metrics and their physical meaning relative to high-grade serous – Type II tissues

From: Stromal alterations in ovarian cancers via wavelength dependent Second Harmonic Generation microscopy and optical scattering

 

μ ′ s

m shape value

FSHG/BSHG

Conversion efficiency

Normal

(≈)

Density

1.32 (++)

Cell and collagen structures more ordered

+

Disordered similar sized collagen fibrils

(- -)

Less collagen organization at fiber level

Benign

(-)

Density

1.01(- - -)

Cell and collagen structures less ordered

(+ +)

Large collagen fibrils

(-)

Less collagen organization at fiber level

Endometrioid - Type I

(- -)

Density

1.40 (+ + +)

Cell and collagen structure more ordered

(+)

Disordered similar sized collagen fibrils

(-)

Decrease collagen density

Low-grade serous – Type I

(-)

Density

1.41 (+ + +)

Cell and collagen structure more ordered

(+ +)

Larger more disordered collagen fibrils

(-)

Less collagen organization at fiber level

  1. (+) slightly increased, (++) moderately increased, (+++) highly increased, (≈) similar valued, (-) slightly decreased, (- -) moderately decreased, (- - -) highly decreased