Table 2 The association analysis between CYFRA21-1 and ADC
No. (%) | |||||
|---|---|---|---|---|---|
Neg | Moderate | High | Total | P Value | |
(1–3 fold) | >3 fold | ||||
(n = 120) | (n = 201) | (n = 124) | (n = 445) | ||
Basic Characteristics | |||||
Age | |||||
< 45 years | 5 (4.2) | 22 (11.0) | 14 (11.3) | 41 | <0.05* |
45–60 years | 57 (47.5) | 66 (32.8) | 38 (30.6) | 161 | |
> 60 years | 58 (48.3) | 113 (56.2) | 72 (58.1) | 243 | |
Sex | |||||
Male | 65 (54.2) | 112 (55.7) | 71 (57.3) | 248 | 0.889 |
Female | 55 (45.8) | 89 (44.3) | 53 (42.7) | 197 | |
Stages | |||||
I + II | 24 (20.0) | 14 (7.0) | 5 (4.0) | 43 | <0.001** |
III + IV | 91 (75.8) | 181 (90.0) | 116 (93.6) | 388 | |
Unknown | 4 (4.2) | 6 (3.0) | 3 (2.4) | 14 | |
Smoke status | |||||
No | 79 (65.9) | 119 (59.2) | 68 (54.8) | 266 | 0.208 |
Yes | 41 (34.1) | 82 (40.8) | 56 (45.2) | 179 | |
Metastasis | |||||
Brain | |||||
No | 107 (89.2) | 164 (81.6) | 95 (76.6) | 366 | <0.05* |
Yes | 13 (10.8) | 37 (18.4) | 29 (23.4) | 79 | |
Bone | |||||
No | 102 (85.0) | 141 (70.1) | 75 (60.5) | 318 | <0.001** |
Yes | 18 (15.0) | 60 (29.9) | 49 (39.5) | 127 | |
Liver | |||||
No | 116 (96.7) | 181 (90.1) | 102 (82.3) | 399 | <0.05* |
Yes | 4 (3.3) | 20 (9.9) | 22 (17.7) | 46 | |
Adrenal gland | |||||
No | 115 (95.8) | 191 (95.0) | 116 (93.5) | 422 | 0.713 |
Yes | 5 (4.2) | 10 (5.0) | 8 (6.5) | 23 | |
Lymph node | |||||
No | 69 (57.5) | 69 (34.3) | 45 (36.3) | 183 | <0.001** |
Yes | 51 (42.5) | 132 (65.7) | 79 (63.7) | 262 | |
Intrapulmonary | |||||
No | 111 (92.5) | 165 (82.1) | 105 (84.7) | 381 | <0.05* |
Yes | 9 (7.5) | 36 (17.9) | 19 (15.3) | 64 | |
Pleural | |||||
No | 103 (85.8) | 161 (80.1) | 88 (71.0) | 352 | <0.05* |
Yes | 17 (14.2) | 40 (19.9) | 36 (29.0) | 93 | |
Mediastinal | |||||
No | 119 (99.2) | 195 (97.0) | 118 (95.2) | 432 | 0.178 |
Yes | 1 (0.8) | 6 (3.0) | 6 (4.8) | 13 | |
Peritoneum | |||||
No | 119 (99.2) | 186 (92.5) | 107 (86.3) | 412 | <0.05* |
Yes | 1 (0.8) | 15 (7.5) | 17 (13.7) | 33 | |