Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma

BMC Cancer

Table 4 The predictive discrimination ability of the nomogram compared to the TNM, BCLC, Okuda, JIS, CLIP, CUPI, and GETCH staging systems in the primary and validation cohorts

	C-index	95% CI for C-index		Goodness of Fit		Comparison of models
	C-index	Lower	Upper	LR	R²	Dxy	SD	Z	p value
Primary cohort (n = 661)
TNM	0.71	0.69	0.73	264.05	0.358	0.40	0.03	13.28	<0.001
BCLC	0.77	0.75	0.79	368.95	0.462	0.20	0.03	5.87	<0.001
Okuda	0.62	0.60	0.65	70.3	0.111	0.55	0.02	23.51	<0.001
JIS	0.73	0.71	0.76	227.23	0.317	0.34	0.03	11.27	<0.001
CLIP	0.76	0.74	0.78	303.8	0.400	0.28	0.03	9.38	<0.001
CUPI	0.68	0.66	0.70	178.33	0.259	0.45	0.03	17.29	<0.001
GETCH	0.65	0.62	0.67	103.83	0.160	0.52	0.02	21.98	<0.001
Nomogram	0.81	0.79	0.82	580.13	0.525	-	-	-	-
Prospective validation cohort (n = 220)
TNM	0.74	0.71	0.77	107.94	0.447	0.12	0.06	2.14	0.035
BCLC	0.77	0.73	0.81	124.83	0.496	0.06	0.05	1.24	0.220
Okuda	0.62	0.57	0.67	20.32	0.105	0.49	0.04	12.07	<0.001
JIS	0.71	0.67	0.76	69.15	0.315	0.31	0.05	6.48	<0.001
CLIP	0.75	0.71	0.80	95.42	0.407	0.13	0.05	2.49	0.014
CUPI	0.64	0.60	0.69	44.17	0.215	0.44	0.04	9.82	<0.001
GETCH	0.65	0.60	0.69	35.99	0.179	0.43	0.05	9.23	<0.001
Nomogram	0.78	0.74	0.82	119.91	0.482	-	-	-	-

ISSN: 1471-2407