Fig. 5
From: Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells
Gastrin induces phosphorylation of the LKB-1-PRKAA2-ULK1 pathway. (a, b and c) Cells were serum starved overnight and treated with gastrin (10 nM). Phosphorylated STK11 (Ser 428), PRKAA2 (Thr 172), ULK1 (Ser 317 & Ser 555), Raptor (Ser 792) and 4EBP1 (Thr 37/46) are shown by immunoblotting. Data was normalised to total protein and immunoblots shown represent one of three independent experiments. Bar graphs (c) represent SEM (n = 3, P-value: *** ≤ 0.01)