Table 4 Concordance of PIK3CA mutation status between endoscopic biopsy and surgically resected specimens
Surgically resected specimens (reference method) | ||||
|---|---|---|---|---|
Wild type | Mutant type | Total | ||
Endoscopic biopsy specimens (trial method) | Wild type | 168 | 2 | 170 |
Mutant type | 1 | 10 | 11 | |
Total | 169 | 12 | 181 | |
Overall concordance rate | 98.3% (95% CI: 95.2–99.7) | |||
Positive concordance rate | 83.3% (95% CI: 51.6–97.9) | |||
Negative concordance rate | 99.4% (95% CI: 96.7–99.9) | |||
Positive predictive value | 90.9% (95% CI: 58.7–99.8) | |||
Negative predictive value | 98.8% (95% CI: 95.8–99.9) | |||