Fig. 3
From: MALAT1 promoted invasiveness of gastric adenocarcinoma
MALAT1 silencing induced apoptosis and cell cycle arrest. AGS and MKN74 cells were transfected with siMALAT1 or siCT, and apoptosis was detected by PI/Annexin V staining (a). Cell cycle arrest was analyzed by PI staining (b). The increased expression of RASSF6 by qRT-PCR and western blot (c). The decreased colony forming rate by siMALAT1_2 compared to siCT (d). The data shown in the panels are representative of three independent experiments. Data shown represent the mean ± s.e.m. Asterisks represent a statistically significant difference from the scrambled control (*P ≤ 0.05)