Fig. 3From: Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancerComparison of tumor LINE-1 methylation levels with the survival of advanced-stage CRC patients. a ROC curve was constructed according to response (CR, PR and SD) or no response (PD) to the FOLFOX regimen. The cut-off value was determined as the point yielding the greatest sum of sensitivity and specificity for prediction of outcome. b, c Kaplan-Meier analysis of progression-free and overall survival of patient groups stratified according to their tumor LINE-1 methylation level. The log-rank test was used for each comparison and p-values are shownBack to article page