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Fig. 3 | BMC Cancer

Fig. 3

From: Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

Fig. 3

Basic mechanism of cyclic nucleotide regulation and function. This cartoon shows basic synthetic and regulatory pathways for cAMP and cGMP. P indicates decreased levels in colorectal neoplasia and C marks increased levels in colorectal neoplasia. *Enzymes with perturbed function in colorectal neoplasia. pGC, particulate guanylyl cyclase; pAC, particulate adenylyl cyclase; sGC, soluble guanylyl cyclase; sAC, soluble adenylyl cyclase; NO, nitric oxide; HCO3, bicarbonate; PDE, phosphodiesterase; Cl−, chloride ion

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BMC Cancer

ISSN: 1471-2407

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