Table 3 Univariable associations of physician readiness to act on genomic risk assessment (GUCY2C) for pN0 colon cancer Patients

 Practice Setting

0.748

  Community-based or Other

24 (58.54)

9 (37.50)

15 (62.50)

.

  Academic Center-based

17 (41.46)

8 (47.06)

9 (52.94)

.

 Age

0.350

  <50

21 (51.22)

7 (33.33)

14 (66.67)

.

  50+

20 (48.78)

10 (50.00)

10 (50.00)

.

 Gender

1.000

  Male

34 (82.93)

14 (41.18)

20 (58.82)

.

  Female

7 (17.07)

3 (42.86)

4 (57.14)

.

 Race

0.103

  (missing/unknown)

1 (.)

1 (.)

.

  Asian

13 (32.50)

3 (23.08)

10 (76.92)

.

  White

27 (67.50)

14 (51.85)

13 (48.15)

.

 Hispanic/Latino

1.000

  No

40 (97.56)

17 (42.50)

23 (57.50)

.

  Yes

1 (2.44)

1 (100.0)

.

 Years in Practice

0.559

  < =10

4 (9.76)

2 (50.00)

2 (50.00)

.

  10–20

11 (26.83)

3 (27.27)

8 (72.73)

.

  >20

26 (63.41)

12 (46.15)

14 (53.85)

.

 Specialty

1.000

  Medical Oncologists+

23 (56.10)

10 (43.48)

13 (56.52)

.

  GI Surgeons

18 (43.90)

7 (38.89)

11 (61.11)

.

 Number of newly diagnosed pN0 colon cancer patients seen in past 12 months

0.679

  <5

6 (14.63)

3 (50.00)

3 (50.00)

.

  5+

35 (85.37)

14 (40.00)

21 (60.00)

.

 Percentage of pN0 colon cancer patients who have had a recurrence in the past 12 months

0.530

  None

20 (48.78)

7 (35.00)

13 (65.00)

.

  1+

21 (51.22)

10 (47.62)

11 (52.38)

.

 On average how many pN0 colon cancer patients do you see each month?

0.499

  <5

28 (68.29)

13 (46.43)

15 (53.57)

.

  5+

13 (31.71)

4 (30.77)

9 (69.23)

.

 Belief in accuracy of histopathology

0.742

  Not Agree

14 (34.15)

5 (35.71)

9 (64.29)

.

  Agree

27 (65.85)

12 (44.44)

15 (55.56)

.

 Belief in accuracy of GUY2C testing

0.012

  Not Agree

17 (41.46)

3 (17.65)

14 (82.35)

.

  Agree

24 (58.54)

14 (58.33)

10 (41.67)

.

 Belief in accuracy of combined histopathology and GUCY2C testing

0.128

  Not Agree

4 (9.76)

4 (100.0)

.

  Agree

37 (90.24)

17 (45.95)

20 (54.05)

.

 Belief in need for a more accurate prognostic test for pN0 colon cancer patients

1.000

  Not Agree

2 (4.88)

1 (50.00)

1 (50.00)

.

  Agree

39 (95.12)

16 (41.03)

23 (58.97)

.

 Belief that current staging methods are not accurate for pN0 colon cancer patients

0.062

  Not Agree

17 (41.46)

4 (23.53)

13 (76.47)

.

  Agree

24 (58.54)

13 (54.17)

11 (45.83)

.

 Accuracy of histopathology alone

0.861

  (missing/unknown)

1 (.)

0 (.)

1 (.)

.

  Very Accurate

6 (15.00)

2 (33.33)

4 (66.67)

.

  Somewhat Accurate

31 (77.50)

14 (45.16)

17 (54.84)

.

  Not Accurate

3 (7.50)

1 (33.33)

2 (66.67)

.

  Don’t Know

0 (0.0)

0 (0.0)

0 (0.0)

 Accuracy of GUCY2C testing alone

0.179

  (missing/unknown)

2 (.)

0 (.)

2 (.)

.

  Very Accurate

6 (15.38)

5 (83.33)

1 (16.67)

.

  Somewhat Accurate

22 (56.41)

9 (40.91)

13 (59.09)

.

  Not Accurate

3 (7.69)

1 (33.33)

2 (66.67)

.

  Don’t Know

8 (20.51)

2 (25.00)

6 (75.00)

.

 Accuracy of combined histopathology and GUCY2C testing

0.084

  (missing/unknown)

1 (.)

0 (.)

1 (.)

.

  Very Accurate

25 (62.50)

14 (56.00)

11 (44.00)

.

  Somewhat Accurate

11 (27.50)

2 (18.18)

9 (81.82)

.

  Not Accurate

0 (0.0)

0 (0.0)

0 (0.0)

  Don’t Know

4 (10.00)

1 (25.00)

3 (75.00)

.

 Stress from uncertainty in decision making about treatment for pN0 colon cancer patients (scale)

0.216

  Not Agree (<=3)

22 (53.66)

7 (31.82)

15 (68.18)

.

  Agree (>3)

19 (46.34)

10 (52.63)

9 (47.37)

.

 Belief that treatment decision making for pN0 colon cancer patients is easy

0.499

  Not Agree

13 (31.71)

4 (30.77)

9 (69.23)

.

  Agree

28 (68.29)

13 (46.43)

15 (53.57)

.

 Confidence in treatment decision making for pN0 colon cancer patients

0.729

  Not Agree

12 (29.27)

4 (33.33)

8 (66.67)

.

  Agree

29 (70.73)

13 (44.83)

16 (55.17)

.

 Belief that treatment choice for pN0 colon cancer patients is clear

0.025

  Not Agree

19 (46.34)

4 (21.05)

15 (78.95)

.

  Agree

22 (53.66)

13 (59.09)

9 (40.91)

.