Table 1 Univariable associations of physician receptivity to genomic risk assessment (GUCY2C) for pN0 colon cancer patients

 Practice Setting

0.004

  Community-based or Other

24 (58.54)

8 (33.33)

16 (66.67)

.

  Academic Center-based

17 (41.46)

14 (82.35)

3 (17.65)

.

 Age

1.000

  <50

21 (51.22)

11 (52.38)

10 (47.62)

.

  50+

20 (48.78)

11 (55.00)

9 (45.00)

.

 Gender

0.219

  Male

34 (82.93)

20 (58.82)

14 (41.18)

.

  Female

7 (17.07)

2 (28.57)

5 (71.43)

.

 Race

1.000

  (missing/unknown)

1 (.)

0 (.)

1 (.)

.

  Asian

13 (32.50)

7 (53.85)

6 (46.15)

.

  White

27 (67.50)

15 (55.56)

12 (44.44)

.

 Hispanic/Latino

0.463

  No

40 (97.56)

22 (55.00)

18 (45.00)

.

  Yes

1 (2.44)

1 (100.0)

.

 Years in Practice

0.891

  < =10

4 (9.76)

2 (50.00)

2 (50.00)

.

  10–20

11 (26.83)

5 (45.45)

6 (54.55)

.

  >20

26 (63.41)

15 (57.69)

11 (42.31)

.

 Specialty

0.758

  Medical Oncologists+

23 (56.10)

13 (56.52)

10 (43.48)

.

  GI Surgeons

18 (43.90)

9 (50.00)

9 (50.00)

.

 Number of newly diagnosed pN0 colon cancer patients seen in past 12 months

0.668

  <5

6 (14.63)

4 (66.67)

2 (33.33)

.

  5+

35 (85.37)

18 (51.43)

17 (48.57)

.

 Percentage of pN0 colon cancer patients who have had a recurrence in the past 12 months

1.000

  None

20 (48.78)

11 (55.00)

9 (45.00)

.

  1+

21 (51.22)

11 (52.38)

10 (47.62)

.

 On average how many pN0 colon cancer patients do you see each month?

0.737

  <5

28 (68.29)

16 (57.14)

12 (42.86)

.

  5+

13 (31.71)

6 (46.15)

7 (53.85)

.

 Belief in accuracy of histopathology

1.000

  Not Agree

14 (34.15)

8 (57.14)

6 (42.86)

.

  Agree

27 (65.85)

14 (51.85)

13 (48.15)

.

 Belief in accuracy of GUY2C testing

0.216

  Not Agree

17 (41.46)

7 (41.18)

10 (58.82)

.

  Agree

24 (58.54)

15 (62.50)

9 (37.50)

.

 Belief in accuracy of combined histopathology and GUCY2C testing

0.038

  Not Agree

4 (9.76)

0 (0.0)

4 (100.0)

.

  Agree

37 (90.24)

22 (59.46)

15 (40.54)

.

 Belief in need for a more accurate prognostic test for pN0 colon cancer patients

1.000

  Not Agree

2 (4.88)

1 (50.00)

1 (50.00)

.

  Agree

39 (95.12)

21 (53.85)

18 (46.15)

.

 Belief that current staging methods are not accurate for pN0 colon cancer patients

0.216

  Not Agree

17 (41.46)

7 (41.18)

10 (58.82)

.

  Agree

24 (58.54)

15 (62.50)

9 (37.50)

.

 Accuracy of histopathology alone

0.388

  (missing/unknown)

1 (.)

0 (.)

1 (.)

.

  Very Accurate

6 (15.00)

3 (50.00)

3 (50.00)

.

  Somewhat Accurate

31 (77.50)

16 (51.61)

15 (48.39)

.

  Not Accurate

3 (7.50)

3 (100.0)

0 (0.0)

.

  Don’t know

0 (0.0)

0 (0.0)

0 (0.0)

.

 Accuracy of GUCY2C testing alone

0.133

  (missing/unknown)

2 (.)

0 (.)

2 (.)

.

  Very Accurate

6 (15.38)

4 (66.67)

2 (33.33)

.

  Somewhat Accurate

22 (56.41)

13 (59.09)

9 (40.91)

.

  Not Accurate

3 (7.69)

3 (100.0)

0 (0.0)

.

  Don’t Know

8 (20.51)

2 (25.00)

6 (75.00)

.

 Accuracy of combined histopathology and GUCY2C testing

0.054

  (missing/unknown)

1 (.)

0 (.)

1 (.)

.

  Very Accurate

25 (62.50)

16 (64.00)

9 (36.00)

.

  Somewhat Accurate

11 (27.50)

6 (54.55)

5 (45.45)

.

  Not Accurate

0 (0.0)

0 (0.0)

0 (0.0)

  Don’t Know

4 (10.00)

0 (0.0)

4 (100.0)

.

 Stress from uncertainty in decision making about treatment for pN0 colon cancer patients (scale)

0.350

  Not Agree (<=3)

22 (53.66)

10 (45.45)

12 (54.55)

.

  Agree (>3)

19 (46.34)

12 (63.16)

7 (36.84)

.

 Belief that treatment decision making for pN0 colon cancer patients is easy

0.009

  Not Agree

13 (31.71)

11 (84.62)

2 (15.38)

.

  Agree

28 (68.29)

11 (39.29)

17 (60.71)

.

 Confidence in treatment decision making for pN0 colon cancer patients

0.325

  Not Agree

12 (29.27)

8 (66.67)

4 (33.33)

.

  Agree

29 (70.73)

14 (48.28)

15 (51.72)

.

 Belief that treatment choice for pN0 colon cancer patients is clear

0.756

  Not Agree

19 (46.34)

11 (57.89)

8 (42.11)

.

  Agree

22 (53.66)

11 (50.00)

11 (50.00)

.