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Table 1 Changes in ER, PR and Ki67 in paired core biopsy/resection specimens (n = 42 women)

From: A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer

 

Number of patients

Change from <4 to ≥4

Change from ≥4 to < 4

Rise of fall in score, but not crossing threshold 4

No change between samples

ER premenopausal

15

0

3

4

8

ER postmenopausal

26

0

1

14

11

PR premenopausala

15

1

4

4

6

PR postmenopausala

16

1

3

6

6

  

Change from <20 % to ≥20 %

Change from ≥20 % to <20 %

Rise or fall in Ki67, but not crossing 20 %

No change between samples

Ki67 premenopausal

15

2

1

8 rise

4

Ki67 postmenopausalb

25

1

4

3 rise + 11 fall

6

  1. Notes
  2. aPR not assessed in the diagnostic core from one premenopausal and nine postmenopausal women
  3. bKi67 not assessed in the diagnostic core from two postmenopausal patients